Stakeholder Panel on Infant Formula and Adult Nutritionals (SPIFAN)


(Carotenoids, Fluoride, and GOS)

April 1, 2019: AOAC INTERNATIONAL (AOAC) invites method developers to submit methods for consideration and possible evaluation through the AOAC Official MethodSM program. Prospective methods must be able to determine Carotenoids (alpha-carotene & lutein), Fluoride, and GOS in all forms of infant, adult, and/or pediatric formula (powders, ready-to-feed liquids, and liquid concentrates) according to each nutrient's standard method performance requirements.

It is expected that multiple methods may be required to meet the standard method performance requirements for Amino Acids.

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to view Standard Method Performance Requirements (SMPR®).

Infant formula is defined as breast-milk substitute specially manufactured to satisfy, by itself, the nutritional requirements of infants during the first months of life up to the introduction of appropriate complementary feeding1. Adult/pediatric formula is defined as nutritionally complete, specially formulated foods, consumed in liquid form, which may constitute the sole source of nourishment2. Acceptable methods must be compatible with formula made from any combination of milk, soy, rice, whey, hydrolyzed protein, starch, and amino acids, with and without intact protein; and with test samples in ready-to-feed liquid, concentrated liquid and powdered form.

The ultimate objective of this project is to select, evaluate, and validate reference methods that can be used for dispute resolution. Acceptable methods must be reliable and reproducible when used by trained analysts in accredited laboratories. Any analytical technique that meets the following method performance requirements is acceptable. Interested method developers must provide their method and data demonstrating that the method can meet the performance requirements.

Methods must be in AOAC OMA report format and MS Word (NO EXCEPTIONS). Please visit the AOAC SPIFAN Resource page for information on method submission. Deadline for all method submissions is August 2, 2019.

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to submit your method(s). (Email submissions will not be accepted)

For general AOAC SPIFAN information or comments, contact Delia Boyd, Senior Manager at or via telephone: 301-924-7077 ext 126.


1Codex Standard 72-1981
2AOAC Stakeholder Panel on Infant Formula and Adult Nutritionals (SPIFAN); 2010